Healthcare Functions of Cordyceps cicadae | Semantic Scholar (2024)

The results suggested that HEA-enriched C. cicadae mycelium produced by liquid fermentation is safe and can be developed as a functional health food.

Findings indicate that the immunity of the host insect and growth environment have a strong impact on the metabolomic variation in Isaria cicadae, and suggests differential utilization value for the insect portions, coremia and mycelia of the fungus.

Spore powder polysaccharides extracted from Cordyceps cicadae effectively improved body weight and glucose and lipid metabolism in type 2 diabetes model mice, in addition to exerting a protective effect on liver injury.

The liquid extracted from C. cicadae BG01 fruiting body neither causes toxicity nor damages to liver and kidney functions of mice at the dose of 250 μL/mouse/day equivalent to 780 mg dried fungus/kg of body weight for 4 weeks.

It is suggested that the therapeutic effect of C. cicadae mycelia may be driven by one of its active components, HEA, which could alleviate many diabetes complications in genetically obese mice and may offer promise as a supplement for diabetes management.

With the discovery of the incredible diversity of entomogenous fungi in Peru, many new candidate species are now being researched for their medicinal properties and the potential for cultivation, in an effort to commercialization as substitutes for increasingly rare O. sinensis.

Results demonstrate that the oral administration of HEA‐enriched C. cicadae mycelia is safe for the central nervous system, cardiovascular system, and respiratory system in ICR male mice via oral gavage administration.

The potential adverse effects of orally administered HEA-enriched C. cicadae mycelia on fertility and early embryonic development to implantation in Sprague-Dawley rats at doses of 500, 1,000, and 1,500 mg/kg were described.

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Renal injury, reflected in urine and serum analyses, and pathological changes induced by SNx were attenuated by TE and AE intervention, and it is shown that C. cicadae could provide a rational strategy for combating renal fibrosis.

It was indicated that Cordyceps cicadae had obvious decrease-sugar effect on no mal mice and diabetic mice made by Alloxan and had significant anti-action to hemorrhagic anemia and anemia caused by being injected phenyl hydrazine hydrochloride.

Paecilomyces cicadidae can activate the AMφ, strengthen immunity, improve lipin metabolism and protect internal organs of rats.

In order to improve the metabolism yield of cordycepin in the strains of Paecilomyces cicadae RCEF1081, the liquid culture technology of it was studied and the total yield could reach as high as 2.7720mg/g and was raised 144% compared with that of before.

ACCSM could relieve the expression of glomerulosclerosis and prevent the progression of chronic renal failure (CRF) and be evaluated by using quantitative analysis method with the analytic system of pathology image.

PCPS could enhance the phagocytizing function of PMphi, AMphi of aged rats in vivo, and strengthen the immune function of spleen and its proliferative activity as well, so that the immunity of aged Rats could be improved.

PcPSt increasd the spleen index of tumor-bearing mice and cooperated with Cy to promote antitumor activity and Paecilomyces cicadidae polysaccharide can promote immunomodulatory and antitumors activity in vivo and in vitro experiments.

The polysaccharide combined with ADM or DDP can not increase their anti-tumor effects in vitro, but adenosine combined withADM can increase anti-Tumor Effects in vitro.

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